Recently the NIH Knockout Mouse Project (KOMP), a trans-NIH initiative, funded by 19 Institutes and Centers, was funded to produce a comprehensive resource of mouse mutant ES cells. The mission of KOMP is to ensure that every gene in the mouse genome has been knocked out, marked with a reporter system of high utility (RFA-HG-05-007) and made publicly available through a KOMP repository (http://www.nih.gov/science/models/mouse/knockout/). The preferred resource would be one in which all of the mutations are carried on a uniform background in strain C57BL/6 because of its broad experimental utility; KOMP aims to produce the majority of the knockouts in this strain (RFA-DA-06-009).
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This site is maintained by the I-DCC and the KOMP-DCC.
Supported by the European Union (Project number: 223592)
and the National Institutes of Health (Grant number: NIH HG004074).