Browsing Data by Marker Symbol: 'K'

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Kcng2

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcng2 was found for the following reasons:

symbol	-	Kcng2
interpro_desc	-	K_chnl_volt-dep_Kv6
marker_symbol_str	-	Kcng2
marker_symbol	-	Kcng2
interpro	-	IPR003969\|\|K_chnl_volt-dep_Kv6\|\|Potassium channel, voltage dependent, Kv6

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily G, member 2 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AA591524
Location:	Chr18:80294544-80364254(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:3694646	Ensembl Gene ID:	ENSMUSG00000059852	Vega Gene ID:
Entrez Gene ID:	240444	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNG2	26251
Rat	Kcng2	307234

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM	VEGA Annotation Requested		Projects: 98585

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	1 strain/ES cell line
International Gene Trap Consortium (IGTC):	1 gene trap
Other mutations in MGI:	1 mutant

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcng3

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcng3 was found for the following reasons:

synonym	-	Kv10.1a
ikmc_project_product_status	-	KOMP-CSD Vector Generated
symbol	-	Kcng3
interpro_desc	-	K_chnl_volt-dep_Kv9
marker_symbol_str	-	Kcng3
marker_symbol	-	Kcng3
ikmc_project_product_status_str	-	KOMP-CSD Vector Generated
ikmc_project	-	KOMP-CSD
allele	-	tm1e(KOMP)Wtsi
interpro	-	IPR003971\|\|K_chnl_volt-dep_Kv9\|\|Potassium channel, voltage dependent, Kv9

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily G, member 3 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	KV6.3, Kv10.1a, Kv10.1b
Location:	Chr17:83585957-83631895(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:2663923	Ensembl Gene ID:	ENSMUSG00000045053	Vega Gene ID:
Entrez Gene ID:	225030	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNG3	170850
Rat	Kcng3	171011

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-CSD (Project: 35048)	order	order	view details

ES Cell Clones

Cassette Type

6 Knockout-First Alleles

9 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0527_3_B09

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_C10

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	fail	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	fail

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_F11

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_G10

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_G12

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_H09

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0527_3_B11

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_B12

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_C12

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_D10

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_D12

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_E09

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_F09

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_F10

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0527_3_H12

PRPGS00171_A_F09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
232094	PRPGS00171_A_F09	PCS00171_A_F09	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view
232094	PRPGS00171_A_F09	PCS00171_A_F09	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	2 strains/ES cell lines
Targeted mutations in MGI:	2 mutants
Other mutations in MGI:	9 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcng4

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcng4 was found for the following reasons:

synonym	-	KV6.3
ikmc_project_product_status	-	KOMP-CSD Vector Generated
symbol	-	Kcng4
interpro_desc	-	K_chnl_volt-dep_Kv9
marker_symbol_str	-	Kcng4
marker_symbol	-	Kcng4
ikmc_project_product_status_str	-	KOMP-CSD Vector Generated
ikmc_project	-	KOMP-CSD
allele	-	tm1(KOMP)Vlcg
interpro	-	IPR003971\|\|K_chnl_volt-dep_Kv9\|\|Potassium channel, voltage dependent, Kv9

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily G, member 4 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	4921535I01Rik, AW049024, KV6.3, KV6.4
Location:	Chr8:119623854-119635680(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1913983	Ensembl Gene ID:	ENSMUSG00000045246	Vega Gene ID:	OTTMUSG00000033798
Entrez Gene ID:	66733	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNG4	93107
Rat	Kcng4	307900

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice

Allele Name

Allele Type

EMMA ID

Colony Prefix

ES Cell/Common Name

Genetic Background

QC/Screening Data

MI/Distribution Centre

currently unavailable

Kcng4^{tm1(KOMP)Vlcg}

Deletion (Promotor Driven Cassette)

BL1272

11043A-F7

C57BL/6NTac;C57BL/6NTac;C57BL/6N

view data
( about )

UCD/

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	na	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	pass
LacZ SR-PCR	na	5' Cassette Integrity		Neo SR-PCR	na
Mutant Specific SR-PCR	na	LoxP Confirmation	na	3' LR-PCR	na
Genotyping Comment

currently unavailable

Kcng4^{tm1(KOMP)Vlcg}

Deletion (Promotor Driven Cassette)

BL1271

11043A-F10

C57BL/6N

view data
( about )

UCD

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	na	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	pass
LacZ SR-PCR	na	5' Cassette Integrity		Neo SR-PCR	na
Mutant Specific SR-PCR	na	LoxP Confirmation	na	3' LR-PCR	na
Genotyping Comment

currently unavailable

Kcng4^{tm1(KOMP)Vlcg}

Deletion (Promotor Driven Cassette)

UCD-11043A-A8-1

11043A-A8

C57BL/6N

view data
( about )

UCD

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	na	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	na
LacZ SR-PCR	na	5' Cassette Integrity		Neo SR-PCR	na
Mutant Specific SR-PCR	na	LoxP Confirmation	na	3' LR-PCR	na
Genotyping Comment

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-Regeneron (Project: VG11043)	order	order	view details

ES Cell Clones

Cassette Type

5 Deletion Alleles

Promotor Driven

Allele:	genbank file
Targeting Vector:	genbank file

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

11043A-A8

VG11043

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

11043A-F10

VG11043

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

11043A-F12

VG11043

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

11043A-F4

VG11043

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

11043A-F7

VG11043

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
	VG11043		ZEN-Ub1		view

	Vectors	ES Cells
EUCOMM (Project: 83862)	order	order	view details

ES Cell Clones

Cassette Type

19 Knockout-First Alleles

0 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Targeting Vector:

genbank file | image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0530_7_C09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_C10

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_C11

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_C12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_D09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_D10

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_D12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_E09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_E10

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_E11

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_E12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_F09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_F12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_G09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_G11

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_G12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_H09

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_H10

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0530_7_H12

PRPGS00115_B_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
111966	PRPGS00115_B_B06	PCS00115_C_B06	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	6 strains/ES cell lines
Targeted mutations in MGI:	2 mutants
Other mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh1

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh1 was found for the following reasons:

synonym	-	Kv10.1
go_ontology	-	-containing groups \| kinase activity \| phosphotransferase activity, alcohol group as acceptor \| molecular transducer
ikmc_project_product_status	-	KOMP-CSD Vector Generated
go_term	-	phosphorelay sensor kinase activity
symbol	-	Kcnh1
interpro_desc	-	K_chnl_volt-dep_EAG
marker_symbol_str	-	Kcnh1
go	-	phosphorelay sensor kinase activity
marker_symbol	-	Kcnh1
ikmc_project_product_status_str	-	KOMP-CSD Vector Generated
ikmc_project	-	KOMP-CSD
interpro	-	IPR003949\|\|K_chnl_volt-dep_EAG\|\|Potassium channel, voltage-dependent, EAG
GO	-	phosphorelay sensor kinase activity

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 1 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	Kv10.1, M-eag, ether a go-go
Location:	Chr1:192190784-192510159(+)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1341721	Ensembl Gene ID:	ENSMUSG00000058248	Vega Gene ID:	OTTMUSG00000024518
Entrez Gene ID:	16510	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH1	3756
Rat	Kcnh1	65198

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice

	Allele Name	Allele Type	EMMA ID	Colony Prefix	ES Cell/Common Name	(International) Strain Designation	QC/Screening Data	MI/Distribution Centre
order	Kcnh1^tm1Lex		EM:02339		LEXKO-1588, CHA302N1	B6;129S5-Kcnh1/Ieg	no data reported ( about )

view original data

Data provided by The European Mouse Mutant Archive (EMMA)

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-CSD	Vector - Initial Attempt Unsuccessful		Projects: 32179

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	3 strains/ES cell lines
International Gene Trap Consortium (IGTC):	2 gene traps
Targeted mutations in MGI:	1 mutant
Other mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh2

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh2 was found for the following reasons:

go_ontology	-	-containing groups \| kinase activity \| phosphotransferase activity, alcohol group as acceptor \| molecular transducer
ikmc_project_product_status	-	KOMP-Regeneron Vector Generated
go_term	-	phosphorelay sensor kinase activity
symbol	-	Kcnh2
interpro_desc	-	K_chnl_volt-dep_EAG/ELK/ERG
marker_symbol_str	-	Kcnh2
go	-	phosphorelay sensor kinase activity
marker_symbol	-	Kcnh2
ikmc_project_product_status_str	-	KOMP-Regeneron Vector Generated
ikmc_project	-	KOMP-Regeneron
interpro	-	IPR003938\|\|K_chnl_volt-dep_EAG/ELK/ERG\|\|Potassium channel, voltage-dependent, EAG/ELK/ERG
GO	-	phosphorelay sensor kinase activity

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 2 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AI326795, ERG1, LQT, Lqt2, M-erg, ether a go-go related, merg1a, merg1b
Location:	Chr5:24319589-24351604(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1341722	Ensembl Gene ID:	ENSMUSG00000038319	Vega Gene ID:	OTTMUSG00000024115
Entrez Gene ID:	16511	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH2	3757
Rat	Kcnh2	117018

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 28300)	order	order	view details

ES Cell Clones

Cassette Type

6 Knockout-First Alleles

2 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0209_1_B09

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_B12

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	pass	Karyotype	pass
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_C09

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_E10

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_F09

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_G09

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0209_1_F10

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0209_1_F11

PGRS0004_A_F05

C57BL/6N

JM8.N4

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
42610	PGRS0004_A_F05	PCS00038_A_D10	L1L2_Bact_P	L4L3_pD223_DTA_spec	view
42610	PGRS0004_A_F05	PCS00038_A_D10	L1L2_Bact_P	L4L3_pD223_DTA_spec	view

	Vectors	ES Cells
KOMP-Regeneron	Targeting Vector QC Completed		Projects: VG17145

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	3 strains/ES cell lines
Targeted mutations in MGI:	4 mutants
Other mutations in MGI:	3 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh3

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh3 was found for the following reasons:

go_ontology	-	-containing groups \| kinase activity \| phosphotransferase activity, alcohol group as acceptor \| molecular transducer
ikmc_project_product_status	-	KOMP-Regeneron Vector Generated
go_term	-	phosphorelay sensor kinase activity
symbol	-	Kcnh3
interpro_desc	-	K_chnl_volt-dep_EAG/ELK/ERG
marker_symbol_str	-	Kcnh3
go	-	phosphorelay sensor kinase activity
marker_symbol	-	Kcnh3
ikmc_project_product_status_str	-	KOMP-Regeneron Vector Generated
ikmc_project	-	KOMP-Regeneron
allele	-	tm1(KOMP)Vlcg
interpro	-	IPR003938\|\|K_chnl_volt-dep_EAG/ELK/ERG\|\|Potassium channel, voltage-dependent, EAG/ELK/ERG
GO	-	phosphorelay sensor kinase activity

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 3 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AU019351, C030044P22Rik, Elk2, Melk2, ether a go-go like
Location:	Chr15:99224976-99242817(+)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1341723	Ensembl Gene ID:	ENSMUSG00000037579	Vega Gene ID:
Entrez Gene ID:	16512	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH3	23416
Rat	Kcnh3	27150

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice

Allele Name

Allele Type

EMMA ID

Colony Prefix

ES Cell/Common Name

Genetic Background

QC/Screening Data

MI/Distribution Centre

contact distributor

Kcnh3^{tm1(KOMP)Vlcg}

Deletion (Promotor Driven Cassette)

JAX-17146A-A5-2

17146A-A5

C57BL/6N;C57BL/6N;C57BL/6N

view data
( about )

JAX/UCD

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	pass	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	pass
LacZ SR-PCR	na	5' Cassette Integrity		Neo SR-PCR	na
Mutant Specific SR-PCR	na	LoxP Confirmation	na	3' LR-PCR	na
Genotyping Comment

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-Regeneron (Project: VG17146)	order	order	view details

ES Cell Clones

Cassette Type

2 Deletion Alleles

Promotor Driven

Allele:	genbank file
Targeting Vector:	genbank file

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

17146A-A5

VG17146

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17146A-C6

VG17146

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
	VG17146		ZEN-Ub1		view

	Vectors	ES Cells
EUCOMM (Project: 48682)	order	order	view details

ES Cell Clones

Cassette Type

2 Knockout-First Alleles

6 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0567_7_F10

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_G11

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0567_7_A09

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_C12

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_E11

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_E12

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_G09

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0567_7_H12

PRPGS00130_B_E10

C57BL/6N-A^tm1Brd/a

JM8A1.N3

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
115571	PRPGS00130_B_E10	PCS00130_B_E10	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view
115571	PRPGS00130_B_E10	PCS00130_B_E10	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	6 strains/ES cell lines
International Gene Trap Consortium (IGTC):	1 gene trap
Targeted mutations in MGI:	7 mutants
Other mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh4

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh4 was found for the following reasons:

go_ontology	-	-containing groups \| kinase activity \| phosphotransferase activity, alcohol group as acceptor \| molecular transducer
ikmc_project_product_status	-	KOMP-CSD Vector Generated
go_term	-	phosphorelay sensor kinase activity
symbol	-	Kcnh4
interpro_desc	-	K_chnl_volt-dep_EAG/ELK/ERG
marker_symbol_str	-	Kcnh4
go	-	phosphorelay sensor kinase activity
marker_symbol	-	Kcnh4
ikmc_project_product_status_str	-	KOMP-CSD Vector Generated
ikmc_project	-	KOMP-CSD
allele	-	tm1a(KOMP)Wtsi
interpro	-	IPR003938\|\|K_chnl_volt-dep_EAG/ELK/ERG\|\|Potassium channel, voltage-dependent, EAG/ELK/ERG
GO	-	phosphorelay sensor kinase activity

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 4 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	BEC2
Location:	Chr11:100740376-100759942(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:2156184	Ensembl Gene ID:	ENSMUSG00000035355	Vega Gene ID:	OTTMUSG00000002129
Entrez Gene ID:	380728	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH4	23415
Rat	Kcnh4	114032

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-CSD (Project: 27894)	order	order	view details

ES Cell Clones

Cassette Type

9 Knockout-First Alleles

2 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0090_4_A07

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	0.6 - 0.51	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	-	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_B07

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	0.7 - 0.61	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	-	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_C09

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_D07

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_F08

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	pass	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_G09

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_H07

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_H08

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	pass	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_H08

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	0.8 - 0.71	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	-	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0090_4_D08

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0090_4_D09

PRPGS00048_A_A07

C57BL/6N

JM8.N19

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
43941	PRPGS00048_A_A07	PCS00048_A_A07	L1L2_Bact_P	R3R4_pBR_amp	view
43941	PRPGS00048_A_A07	PCS00048_A_A07	L1L2_Bact_P	R3R4_pBR_amp	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	2 strains/ES cell lines
Targeted mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh5

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh5 was found for the following reasons:

go_ontology	-	-containing groups \| kinase activity \| phosphotransferase activity, alcohol group as acceptor \| molecular transducer
ikmc_project_product_status	-	KOMP-Regeneron Vector Generated
go_term	-	phosphorelay sensor kinase activity
symbol	-	Kcnh5
interpro_desc	-	K_chnl_volt-dep_EAG
marker_symbol_str	-	Kcnh5
go	-	phosphorelay sensor kinase activity
marker_symbol	-	Kcnh5
ikmc_project_product_status_str	-	KOMP-Regeneron Vector Generated
ikmc_project	-	KOMP-Regeneron
allele	-	tm1(KOMP)Vlcg
interpro	-	IPR003949\|\|K_chnl_volt-dep_EAG\|\|Potassium channel, voltage-dependent, EAG
GO	-	phosphorelay sensor kinase activity

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 5 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:
Location:	Chr12:74897217-75177332(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:3584508	Ensembl Gene ID:	ENSMUSG00000034402	Vega Gene ID:
Entrez Gene ID:	238271	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH5	27133
Rat	Kcnh5	171146

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 45814)	order	order	view details

ES Cell Clones

Cassette Type

5 Knockout-First Alleles

1 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0637_4_A10

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0637_4_D11

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0637_4_D12

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0637_4_H11

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0637_4_H12

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0637_4_G11

PG00149_Z_5_B09

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
179661	PG00149_Z_5_B09	PCTS00149_A_E04	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view
179661	PG00149_Z_5_B09	PCTS00149_A_E04	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view

	Vectors	ES Cells
KOMP-Regeneron (Project: VG18875)	order	order	view details

ES Cell Clones

Cassette Type

1 Deletion Alleles

Promotor Driven

Allele:	genbank file
Targeting Vector:	genbank file

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

18875A-H2

VG18875

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
	VG18875		ZEN-Ub1		view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	5 strains/ES cell lines
Targeted mutations in MGI:	5 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh6

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh6 was found for the following reasons:

ikmc_project_product_status	-	KOMP-Regeneron Vector Generated
symbol	-	Kcnh6
interpro_desc	-	K_chnl_volt-dep_EAG/ELK/ERG
marker_symbol_str	-	Kcnh6
marker_symbol	-	Kcnh6
ikmc_project_product_status_str	-	KOMP-Regeneron Vector Generated
ikmc_project	-	KOMP-Regeneron
allele	-	tm1(KOMP)Vlcg
interpro	-	IPR003938\|\|K_chnl_volt-dep_EAG/ELK/ERG\|\|Potassium channel, voltage-dependent, EAG/ELK/ERG

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 6 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	m-erg2
Location:	Chr11:106008124-106034549(+)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:2684139	Ensembl Gene ID:	ENSMUSG00000001901	Vega Gene ID:	OTTMUSG00000002939
Entrez Gene ID:	192775	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH6	81033
Rat	Kcnh6	116745

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-Regeneron (Project: VG17147)	order	order	view details

ES Cell Clones

Cassette Type

6 Deletion Alleles

Promotor Driven

Allele:	genbank file
Targeting Vector:	genbank file

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

17147A-A9

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17147A-B6

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17147A-D10

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17147A-E3

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17147A-G12

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

17147A-H2

VG17147

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
	VG17147		ZEN-Ub1		view

	Vectors	ES Cells
EUCOMM (Project: 27007)	order	order	view details

ES Cell Clones

Cassette Type

0 Knockout-First Alleles

1 Targeted Non-Conditional Alleles

Promotorless

Targeting Vector:

genbank file | image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0009_2_A03

PGS00004_A_D02

129S7

AB2.2

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotorless Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
111	PGS00004_A_D02	PCS00004_A_D02	L1L2_gt0	L3L4_pZero_DTA_kan	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	10 strains/ES cell lines
International Gene Trap Consortium (IGTC):	1 gene trap
Targeted mutations in MGI:	3 mutants
Other mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

Kcnh7

Datasets: Gene Details Europhenome Mice IKMC Vectors and ES Cells Other Mutants/Resources

Kcnh7 was found for the following reasons:

synonym	-	Kv11.3
symbol	-	Kcnh7
interpro_desc	-	K_chnl_volt-dep_EAG/ELK/ERG
marker_symbol_str	-	Kcnh7
marker_symbol	-	Kcnh7
ikmc_project	-	KOMP-Regeneron
interpro	-	IPR003938\|\|K_chnl_volt-dep_EAG/ELK/ERG\|\|Potassium channel, voltage-dependent, EAG/ELK/ERG

Gene Details

Marker Name(s):	potassium voltage-gated channel, subfamily H (eag-related), member 7 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	9330137I11Rik, Kv11.3, erg3
Location:	Chr2:62693414-63184287(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:2159566	Ensembl Gene ID:	ENSMUSG00000059742	Vega Gene ID:	OTTMUSG00000012800
Entrez Gene ID:	170738	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	KCNH7	90134
Rat	Kcnh7	170739

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

Europhenome no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 47180)	order	order	view details

ES Cell Clones

Cassette Type

2 Knockout-First Alleles

0 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Targeting Vector:

genbank file | image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0694_1_B04

PG00183_Z_6_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0694_1_E01

PG00183_Z_6_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
181996	PG00183_Z_6_B06	PCS00183_A_F08	L1L2_Bact_P	L3L4_pD223_DTA_spec	view

	Vectors	ES Cells
KOMP-Regeneron	Design Finished/Oligos Ordered		Projects: VG18876

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

Other Mutants/Resources

International Mouse Strain Resource (IMSR):	4 strains/ES cell lines
Targeted mutations in MGI:	2 mutants

view original data

Data provided by Mouse Genome Informatics (MGI)

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Available Products

Mammalian Phenotype

Chromosome

Marker Symbol