IKMC Project Report - EUCOMM (ID: 114109)

Glrx5 MGI:1920296 ENSMUSG00000021102
Pre-pipeline Designs Vectors ES Cells Mice
Vector Unsuccessful - Project Terminated

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000021522 protein_coding Residual N-terminal, novel C-terminal product view

Predicted translation:

MSASLSRAAAALLRWGRSAGGGGLPGAGVRAASSGGQAEQLDALVKKDKVVVFLKVLKTTPTGQPSRKCTSTASLWGAVT
SFCRCIRMGT*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000114617 Glutaredoxin (5/66 aa) UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000114617 Glutaredoxin (40/66 aa) CDS Deleted
ENSMUSE00000114619 Glutaredoxin (22/66 aa) CDS + stop codon + UTR CDS + stop codon + UTR
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available