IKMC Project Report - EUCOMM (ID: 114510)

Nudt19 MGI:94203 ENSMUSG00000034875 OTTMUSG00000026112
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 3 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000040962 protein_coding Residual C-terminal product view

Predicted translation:

MRRLENFASLSALYRFCSDRPSEVPEKWLPIILLTSDGTIHLLPGDELYVKDSDFLEKNMSTDKKTEEIVKEGKVLNRVV
IHSPYVYEIYMTLPSENKHVYPRNYIVNKRCTAHL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000396831 NUDIX_hydrolase_dom (70/235 aa) UTR + start codon + CDS UTR
ENSMUSE00000396831 NUDIX_hydrolase_dom (210/235 aa) CDS Deleted
ENSMUSE00000296386 NUDIX_hydrolase_dom (25/235 aa) CDS UTR + start codon + CDS
ENSMUSE00000410520 CDS + stop codon + UTR CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000123469 retained_intron Target region does not overlap transcript
ENSMUST00000142930 processed_transcript No analysis available: incomplete transcript
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available