This gene has 7 wild type transcripts,
of which 4 are protein-coding.
Following removal of the floxed region, 4
transcripts are
predicted to produce a truncated protein product of which
0 may be subject to non-sense mediated decay (NMD).
The original allele for this mutation is of type ''. The table below
shows the predicted structure of the gene transcripts after application of Flp and Cre
(forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found
here).
Click the 'view' button for each transcript to see the full prediction for that transcript.
| Ensembl transcript id |
Ensembl Biotype |
Floxed transcript description |
Details |
|
ENSMUST00000154208
|
protein_coding |
Residual N-terminal, novel C-terminal product |
view
|
|
Predicted translation:
MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETT
EEIRQMGTECHYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWVSQPLPA
TEARDSSPEDGRCCATKPGPSLAPVDHEYPHYLEKHTPTSCTGGDSQVLGDLHLYEHL*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000171001
|
protein_coding |
Residual N-terminal, novel C-terminal product |
view
|
|
Predicted translation:
MVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQM
AKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWVSQPLPATEARDSSPEDGRCCATKPGPSLAPVD
HEYPHYLEKHTPTSCTGGDSQVLGDLHLYEHL*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000105744
|
protein_coding |
Residual N-terminal, novel C-terminal product |
view
|
|
Predicted translation:
MVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQM
AKAVREKVSQPLPATEARDSSPEDGRCCATKPGPSLAPVDHEYPHYLEKHTPTSCTGGDSQVLGDLHLYEHL*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000142808
|
protein_coding |
No analysis available: incomplete transcript |
|
|
ENSMUST00000084184
|
nonsense_mediated_decay |
No protein product (NMD) |
view
|
|
Predicted translation:
MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETT
EEIRQMGTECHYFICDVGNREEVYQMAKAVREKTQLVWHQRHL*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000128926
|
processed_transcript |
No analysis available: incomplete transcript |
|
|
ENSMUST00000133265
|
retained_intron |
No analysis available: incomplete transcript |
|
show/hide more transcripts