IKMC Project Report - EUCOMM (ID: 116957)

Slc52a2 MGI:1289288 ENSMUSG00000022560
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000023220 protein_coding Residual N-terminal, unknown C-terminal view

Predicted translation:

MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYLSVLVALGNLGLLLVTLWRRLARGKGEQVP
IRVVQGLGIVGTGLLASLWNHVAPVAGKPYSVAFLTLAFVLALACCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCV
LALGQGVGRLECLHVPANRTTGPPIEVSPINFPERFSATTFFWVLTALLGTSAAAFQGLLLLLPSPTSEPTT

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000623052 UTR UTR
ENSMUSE00000128334 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000128335 CDS CDS
ENSMUSE00000128335 Endogenous_retrovirus_rcpt (62/100 aa) CDS Deleted
ENSMUSE00000128332 Endogenous_retrovirus_rcpt (39/100 aa) CDS Deleted
ENSMUSE00000367330 CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available