IKMC Project Report - EUCOMM (ID: 116970)

Trex1 MGI:1328317 ENSMUSG00000049734 OTTMUSG00000020568
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 3 wild type transcripts, of which 3 are protein-coding. Following removal of the floxed region, 3 transcripts are predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000061973 protein_coding No protein product view

Predicted translation:

MTPAGVEMAPMVQHGLTDPAPWSHADPHLLRPGSHWPAFVSARSHRAVPAGCPQTCSGEHFHFS

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000370054 UTR UTR + start codon + CDS
ENSMUSE00000342118 UTR + start codon + CDS CDS + stop codon + UTR
ENSMUSE00000342118 CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted
ENSMUST00000112053 protein_coding No protein product view

Predicted translation:

MGSQTLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQ

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000690273 UTR UTR
ENSMUSE00000896635 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000896635 CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted
ENSMUST00000128062 protein_coding No protein product view

Predicted translation:

MPGVSMLIRALPDVTDCEEAALDDLCAAETDLEDSEMDCN*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000786107 UTR UTR + start codon + CDS
ENSMUSE00000783371 UTR CDS + stop codon + UTR
ENSMUSE00000793115 UTR + start codon + CDS UTR
ENSMUSE00000793115 CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available