IKMC Project Report - EUCOMM (ID: 117309)

Tsr3 MGI:1915577 ENSMUSG00000015126
Pre-pipeline Designs Vectors ES Cells Mice
Design Requested

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 1 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000063574 protein_coding No protein product (NMD) view

Predicted translation:

MGRKKVARGSRKESGRVRRPSGRSLDAFAEEVGAALRASVQPEEAEDQGGPGPAALPCALAMWELGHCDPKRCTGRKLAR
LGLVRCLRLSQRFGGLVLSPVGTEYVSPADRLFRPCCHFASEV*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000611241 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000551344 DUF367 (15/127 aa) | RNaseL-inhib_metal-bd_dom (32/32 aa) CDS CDS
ENSMUSE00000432609 DUF367 (66/127 aa) CDS Deleted
ENSMUSE00000432601 DUF367 (48/127 aa) CDS CDS + stop codon + UTR
ENSMUSE00000139078 CDS
ENSMUSE00000432586 CDS + stop codon + UTR
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available