This gene has 6 wild type transcripts,
of which 5 are protein-coding.
Following removal of the floxed region, 5
transcripts are
predicted to produce a truncated protein product of which
4 may be subject to non-sense mediated decay (NMD).
The original allele for this mutation is of type ''. The table below
shows the predicted structure of the gene transcripts after application of Flp and Cre
(forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found
here).
Click the 'view' button for each transcript to see the full prediction for that transcript.
| Ensembl transcript id |
Ensembl Biotype |
Floxed transcript description |
Details |
|
ENSMUST00000154335
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MAWRYSQLLLVPVQLVFLASVCCPGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTSPINPSFAD
DCSAPRKHSSHHLYALPSSDYLSRGDH*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000059873
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MAWRYSQLLLVPVQLVFLASVCCPGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTSPINPSFAD
DCSAPRKHSHHLYALPSSDYLSRGDH*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000125426
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MAWRYSQLLLVPVQLVFLASGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTSPINPSFADDCSA
PRKHSHHLYALPSSDYLSRGDH*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000136272
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MAWRYSQLLLVPVQLVFLASVCCPGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTSPINPSFAD
DCSAPRKHSSDYLSRGDH*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000153420
|
protein_coding |
Residual N-terminal, novel C-terminal product |
view
|
|
Predicted translation:
MAWRYSQLLLVPVQLVFLASVCCPGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTSPINPSFAD
DCSAPRKHSHHLYALPSSDYLSRGDH*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000153131
|
retained_intron |
Target region does not overlap transcript |
|
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