IKMC Project Report - EUCOMM (ID: 117690)

Fibcd1 MGI:2138953 ENSMUSG00000026841 OTTMUSG00000012076
Pre-pipeline Designs Vectors ES Cells Mice
Design Completed

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 1 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000028188 protein_coding No protein product (NMD) view

Predicted translation:

MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALV
TVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLR
KGHSLLGQGLSTLQSEQGRLIQALGRGTAWMFS*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000414717 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000371597 CDS CDS
ENSMUSE00000279271 CDS Deleted
ENSMUSE00000163444 Fibrinogen_a/b/g_C (42/217 aa) CDS CDS + stop codon + UTR
ENSMUSE00000279255 Fibrinogen_a/b/g_C (33/217 aa) CDS
ENSMUSE00000279249 Fibrinogen_a/b/g_C (61/217 aa) CDS
ENSMUSE00000409366 Fibrinogen_a/b/g_C (83/217 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available