IKMC Project Report - EUCOMM (ID: 117704)

Ap2s1 MGI:2141861 ENSMUSG00000008036 OTTMUSG00000022892
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000086112 protein_coding Residual N-terminal, unknown C-terminal view

Predicted translation:

MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVE

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000599786 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000336284 AP_mu_sigma_su (50/141 aa) CDS CDS
ENSMUSE00000197995 AP_mu_sigma_su (38/141 aa) CDS Deleted
ENSMUSE00001015972 AP_mu_sigma_su (20/141 aa) CDS Deleted
ENSMUSE00000361197 AP_mu_sigma_su (33/141 aa) CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted
ENSMUST00000141496 retained_intron No analysis available: incomplete transcript
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available