IKMC Project Report - KOMP-CSD (ID: 118466)

Tbrg1 MGI:1100877 ENSMUSG00000011114 OTTMUSG00000029970
Pre-pipeline Designs Vectors ES Cells Mice
Vector Complete

Mice no data available

Mutagenesis Predictions

This gene has 5 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 1 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000117654 protein_coding No protein product (NMD) view

Predicted translation:

MSVLSGLASEPRTPLSSKARMKRLPRKSQNEKYRLKYLRLRRAAKATVFILAEEAPPDTCSN*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000380675 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000216975 CDS Deleted
ENSMUSE00000349122 CDS CDS + stop codon + UTR
ENSMUSE00000378448 FYrich_N (9/52 aa) CDS
ENSMUSE00000406595 FYrich_N (43/52 aa) | FYrich_C (3/83 aa) CDS
ENSMUSE00000216963 FYrich_C (33/83 aa) CDS
ENSMUSE00000402775 FYrich_C (38/83 aa) CDS
ENSMUSE00000354216 FYrich_C (11/83 aa) CDS
ENSMUSE00000366959 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000086066 protein_coding No analysis available: incomplete transcript
ENSMUST00000134711 retained_intron No analysis available: incomplete transcript
ENSMUST00000142736 retained_intron No analysis available: incomplete transcript
ENSMUST00000126062 retained_intron No analysis available: incomplete transcript
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available