IKMC Project Report - EUCOMM (ID: 119908)

Exoc3l2 MGI:1921713 ENSMUSG00000011263 OTTMUSG00000033723
Pre-pipeline Designs Vectors ES Cells Mice
ES Cells - No QC Positives

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000011407 protein_coding Residual N-terminal, novel C-terminal product view

Predicted translation:

MQDEPYQVLVAELHRRALVEYVRPLLRGRLRCRSARTRSRVAGRLREDAAQCSGCFGGWRKHVAALLDIRGLRNTAARQE
ILAVARDLELSESGALPPSRDRAFFADIPVPRTSFCLGLPLLLGRLPVSRLARPNLACLPLRPRPPSPVRARADR*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000771975 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000372897 CDS CDS
ENSMUSE00000412514 CDS CDS
ENSMUSE00001014217 CDS Deleted
ENSMUSE00000981164 CDS + stop codon + UTR CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000137613 protein_coding Residual N-terminal, novel C-terminal product view

Predicted translation:

MRRKWLSSSEALDGIVGTLGAQALALRRMQDEPYQVLVAELHRRALVEYVRPLLRGRLRCRSARTRSRVAGRLREDAAQL
QRLFRRLAEACGSPP*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000771975 Sec6 (33/161 aa) UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000837995 Sec6 (52/161 aa) CDS CDS
ENSMUSE00001037745 Sec6 (41/161 aa) CDS Deleted
ENSMUSE00001070372 Sec6 (36/161 aa) CDS + stop codon + UTR CDS + stop codon + UTR
Legend: in frame deleted frameshifted
show/hide more transcripts

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available