This gene has 7 wild type transcripts,
of which 4 are protein-coding.
Following removal of the floxed region, 4
transcripts are
predicted to produce a truncated protein product of which
4 may be subject to non-sense mediated decay (NMD).
The original allele for this mutation is of type ''. The table below
shows the predicted structure of the gene transcripts after application of Flp and Cre
(forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found
here).
Click the 'view' button for each transcript to see the full prediction for that transcript.
| Ensembl transcript id |
Ensembl Biotype |
Floxed transcript description |
Details |
|
ENSMUST00000162650
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLY
LSPYLMIATCEPNHTWVPISDAGCIIIT*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000160817
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLY
LSPYLMIATCEPNHTWVPISDAGCIIIT*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000016637
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLY
LSPYLMIATCEPNHTWVPISDAGCIIIT*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000162614
|
protein_coding |
No protein product (NMD) |
view
|
|
Predicted translation:
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLY
LSPYLMIATCEPNHTWVPISDAGCIIIT*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000159563
|
nonsense_mediated_decay |
No protein product (NMD) |
view
|
|
Predicted translation:
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLY
LSPYLMIATCEPNHTWVPISDAGCIIIT*
| Legend: |
|
in frame |
|
deleted |
|
frameshifted |
|
|
ENSMUST00000161772
|
retained_intron |
Target region does not overlap transcript |
|
|
ENSMUST00000162951
|
retained_intron |
Target region does not overlap transcript |
|
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