IKMC Project Report - (ID: 49039)

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Pre-pipeline Designs Vectors ES Cells Mice

Mice no data available

Mutagenesis Predictions

This gene has 8 wild type transcripts, of which 5 are protein-coding. Following removal of the floxed region, 5 transcripts are predicted to produce a truncated protein product of which 3 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000038709 protein_coding No protein product (NMD) view

Predicted translation:

MYMQVETRTSTRLHLKRAPGIRSWSLLVGILSTGLAAAYYSGDSLGWKLFYVTGCLFVAVQNLEDWEWWFC*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000381509 UTR UTR
ENSMUSE00001046250 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000964527 CDS CDS
ENSMUSE00001073526 CDS CDS
ENSMUSE00000985757 CDS Deleted
ENSMUSE00001012052 CDS CDS + stop codon + UTR
ENSMUSE00000519562 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000106115 protein_coding No protein product (NMD) view

Predicted translation:

MYMQVETRTSTRLHLKRAPGIRSWSLLVGILSTGLAAAYYSGDSLGWKLFYVTGCLFVAVQNLEDWEWWFC*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000668639 UTR UTR
ENSMUSE00001046250 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000964527 CDS CDS
ENSMUSE00001073526 CDS CDS
ENSMUSE00000985757 CDS Deleted
ENSMUSE00001012052 CDS CDS + stop codon + UTR
ENSMUSE00000519562 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000137299 protein_coding No protein product (NMD) view

Predicted translation:

MYMQVETRTSTRLHLKRAPGIRSWSLLVGILSTGLAAAYYSGDSLGWKLFYVTGCLFVAVQNLEDWEWWFC*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000740502 UTR UTR
ENSMUSE00001046250 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000964527 CDS CDS
ENSMUSE00001073526 CDS CDS
ENSMUSE00000985757 CDS Deleted
ENSMUSE00001012052 CDS CDS + stop codon + UTR
ENSMUSE00000963355 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000147490 protein_coding No analysis available: incomplete transcript
ENSMUST00000169393 protein_coding No analysis available: incomplete transcript
ENSMUST00000156214 nonsense_mediated_decay Target region does not overlap transcript
ENSMUST00000133535 retained_intron No analysis available: incomplete transcript
ENSMUST00000149351 retained_intron No analysis available: incomplete transcript
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available