IKMC Project Report - NorCOMM (ID: 65765)

Cxadr MGI:1201679 ENSMUSG00000022865 OTTMUSG00000014961
Pre-pipeline Designs Vectors ES Cells Mice
ES Cells - No QC Positives

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 2 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000023572 protein_coding No protein product (NMD) view

Predicted translation:

MARLLCFVLLCGIADFTSGLSITTPEQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQIVDQVK*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000836949 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000556946 Ig_V-set (48/108 aa) | Ig_I-set (49/117 aa) CDS CDS
ENSMUSE00000300045 Ig_V-set (60/108 aa) | Ig_I-set (68/117 aa) CDS Deleted
ENSMUSE00000131415 Ig_I-set (38/77 aa) CDS Deleted
ENSMUSE00000131419 Ig_I-set (40/77 aa) CDS CDS + stop codon + UTR
ENSMUSE00000131417 CDS
ENSMUSE00000300029 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000114229 protein_coding No protein product (NMD) view

Predicted translation:

MARLLCFVLLCGIADFTSGLSITTPEQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQIVDQVK*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000642591 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000556946 Ig_V-set (48/108 aa) | Ig_I-set (49/117 aa) CDS CDS
ENSMUSE00000300045 Ig_V-set (60/108 aa) | Ig_I-set (68/117 aa) CDS Deleted
ENSMUSE00000131415 Ig_I-set (38/77 aa) CDS Deleted
ENSMUSE00000131419 Ig_I-set (40/77 aa) CDS CDS + stop codon + UTR
ENSMUSE00000131417 CDS
ENSMUSE00000698587 CDS
ENSMUSE00000698586 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
show/hide more transcripts

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available