IKMC Project Report - KOMP-CSD (ID: 74164)

Stra13 MGI:894324 ENSMUSG00000025144 OTTMUSG00000004086
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 5 wild type transcripts, of which 4 are protein-coding. Following removal of the floxed region, 4 transcripts are predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000055424 protein_coding Novel C-terminal product view

Predicted translation:

MGRSQQLLPPRVLARQVQGKVNQPASRHSPPPAPSSLAL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000403419 UTR + start codon + CDS
ENSMUSE00001052696 CENP-S_centromere_X (18/70 aa) CDS Deleted
ENSMUSE00001073565 CENP-S_centromere_X (19/70 aa) CDS Deleted
ENSMUSE00001089981 CENP-S_centromere_X (30/70 aa) CDS Deleted
ENSMUSE00001018413 CENP-S_centromere_X (4/70 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000106155 protein_coding Novel C-terminal product view

Predicted translation:

MGRSQQLLPPRVLARQVQGKVNQPASRHSPPPAPSSLAL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00001011869 UTR + start codon + CDS
ENSMUSE00000668808 CDS Deleted
ENSMUSE00001059046 CDS Deleted
ENSMUSE00001030498 CDS Deleted
ENSMUSE00000976352 CDS Deleted
ENSMUSE00001043458 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000106154 protein_coding Novel (out of frame) product view

Predicted translation:

MGRSQQLLPPRVLARQVQGKVNQPASRHSPPPAPSSLAL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000993930 UTR UTR
ENSMUSE00000668795 UTR + start codon + CDS Deleted
ENSMUSE00001052696 CENP-S_centromere_X (17/69 aa) CDS Deleted
ENSMUSE00001073565 CENP-S_centromere_X (19/69 aa) CDS Deleted
ENSMUSE00001089981 CENP-S_centromere_X (30/69 aa) CDS Deleted
ENSMUSE00001018413 CENP-S_centromere_X (4/69 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000026137 protein_coding Novel C-terminal product view

Predicted translation:

MGRSQQLLPPRVLARQVQGKVNQPASRHSPPPAPSSLAL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000403419 UTR + start codon + CDS
ENSMUSE00000417220 CENP-S_centromere_X (17/51 aa) CDS Deleted
ENSMUSE00001089981 CENP-S_centromere_X (30/51 aa) CDS Deleted
ENSMUSE00000803864 CENP-S_centromere_X (4/51 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000128543 processed_transcript No analysis available: incomplete transcript
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available