IKMC Project Report - KOMP-CSD (ID: 90023)
Gpx3 MGI:105102 ENSMUSG00000018339 OTTMUSG00000006337
Mice no data available
Mutagenesis Predictions
This gene has 3 wild type transcripts, of which 3 are protein-coding. Following removal of the floxed region, 3 transcripts are predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type 'Knockout-First - Reporter Tagged Insertion'. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.
| Ensembl transcript id | Ensembl Biotype | Floxed transcript description | Details | |||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ENSMUST00000082430 | protein_coding | Residual N-terminal, unknown C-terminal | view | |||||||||||||||||||||||||||||||||||
|
Predicted translation: MARILRASCLLSLLLAGFVPPGRGQEKSK
|
||||||||||||||||||||||||||||||||||||||
| ENSMUST00000149324 | protein_coding | Residual N-terminal, unknown C-terminal | view | |||||||||||||||||||||||||||||||||||
|
Predicted translation: MARILRASCLLSLLLAGFVPPGRGQEKSK
|
||||||||||||||||||||||||||||||||||||||
| ENSMUST00000125094 | protein_coding | Residual N-terminal, unknown C-terminal | view | |||||||||||||||||||||||||||||||||||
|
Predicted translation: MARILRASCLLSLLLAGFVPPGRGQEKSK
|
||||||||||||||||||||||||||||||||||||||
ES Cell Clones no data available
Targeting Vectors
| Genome Browsers: | Ensembl (mouse) - UCSC (mouse) |
|---|---|
| Tools: | LRPCR Genotyping Primers |
| Design ID | Vector Type | Targeting Vector | Cassette | Backbone | Genbank File | |
|---|---|---|---|---|---|---|
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_4_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_8_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_7_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_1_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_3_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_6_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PRPGS00233_A_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_2_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
| order | 357974 | Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette) | PG00233_Z_5_G09 | L1L2_Bact_P | R3R4_pBR_DTA+_Bsd_amp | view |
Intermediate Vectors
| Design ID | Vector Type | Intermediate Vector |
|---|---|---|
| 357974 | Knockout-First - Reporter Tagged Insertion | PCS00233_A_G09 |