IKMC Project Report - (ID: 92093)

non-BioMart die(): Cannot write to '/nfs/team87/services/biomart/ikmc-mart/production/server/releases/20110531105342/logs/log4perl_log': at /software/team87/brave_new_world/lib/perl5/Log/Log4perl/Appender/File.pm line 245.
Pre-pipeline Designs Vectors ES Cells Mice

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 2 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000079659 protein_coding No protein product (NMD) view

Predicted translation:

MADKTPGGSQKASSKNRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESSRESLCDSPHQNLSRPLLENK
LKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKDEHETDEKRGKIYKP
SSRFADQKNPPNQSSNERPPSLLVIETKKPNSGRT*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000219473 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000219468 CDS CDS
ENSMUSE00000219475 CDS CDS
ENSMUSE00000219477 CDS CDS
ENSMUSE00000219474 CDS CDS
ENSMUSE00000219470 CDS CDS
ENSMUSE00000513442 CDS Deleted
ENSMUSE00000219471 CDS CDS + stop codon + UTR
ENSMUSE00000219469 CDS
ENSMUSE00000219476 RRM_dom (8/73 aa) CDS
ENSMUSE00000693972 RRM_dom (56/73 aa) CDS
ENSMUSE00000517875 RRM_dom (10/73 aa) CDS
ENSMUSE00000518756 CDS
ENSMUSE00000521498 Surp (29/46 aa) CDS
ENSMUSE00000514792 Surp (18/46 aa) CDS
ENSMUSE00000492023 CDS
ENSMUSE00000492971 CDS
ENSMUSE00000493903 CDS
ENSMUSE00000502555 CDS
ENSMUSE00000496222 CDS
ENSMUSE00000497069 CDS
ENSMUSE00000498028 CDS
ENSMUSE00000491092 CDS
ENSMUSE00000501266 CDS
ENSMUSE00000502185 CDS
ENSMUSE00000374453 CDS
ENSMUSE00000415159 CDS
ENSMUSE00000415153 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000078374 protein_coding No protein product (NMD) view

Predicted translation:

MADKTPGGSQKASSKNRSSDVHSSGSSDAHPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAF
EGSDGNKVKTFVRGGVVNAAKDEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPNSGRT*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000219473 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000219468 CDS CDS
ENSMUSE00000219477 CDS CDS
ENSMUSE00000219474 CDS CDS
ENSMUSE00000219470 CDS CDS
ENSMUSE00000513442 CDS Deleted
ENSMUSE00000219471 CDS CDS + stop codon + UTR
ENSMUSE00000219469 CDS
ENSMUSE00000219476 RRM_dom (8/73 aa) CDS
ENSMUSE00000693972 RRM_dom (56/73 aa) CDS
ENSMUSE00000517875 RRM_dom (10/73 aa) CDS
ENSMUSE00000518756 CDS
ENSMUSE00000521498 Surp (29/46 aa) CDS
ENSMUSE00000514792 Surp (18/46 aa) CDS
ENSMUSE00000492023 CDS
ENSMUSE00000492971 CDS
ENSMUSE00000493903 CDS
ENSMUSE00000502555 CDS
ENSMUSE00000496222 CDS
ENSMUSE00000497069 CDS
ENSMUSE00000498028 CDS
ENSMUSE00000491092 CDS
ENSMUSE00000501266 CDS
ENSMUSE00000502185 CDS
ENSMUSE00000374453 CDS
ENSMUSE00000415159 CDS
ENSMUSE00000415153 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
show/hide more transcripts

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available