IKMC Project Report - (ID: 93510)

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Pre-pipeline Designs Vectors ES Cells Mice

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 0 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000070875 protein_coding Residual N-terminal, unknown C-terminal view

Predicted translation:

METLESQTGLMVACYHGFGSIVALLSCCPFLDVNQQDKDGNTALMLAAQAGHMSLVTLLLNYFAGLDLERRDQRGLTALM
KAAIQDRSECVVALLMA

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000985603 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000963582 Ankyrin_rpt (12/29 aa) CDS CDS
ENSMUSE00000336471 Ankyrin_rpt (18/29 aa) | Ankyrin_rpt (23/31 aa) CDS CDS + stop codon + UTR
ENSMUSE00000454701 Ankyrin_rpt (9/31 aa) CDS + stop codon + UTR Deleted
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available