IKMC Project Report - EUCOMM (ID: 98578)

Jakmip2 MGI:1923467 ENSMUSG00000024502
Pre-pipeline Designs Vectors ES Cells Mice
Design Completed

Mice no data available

Mutagenesis Predictions

This gene has 1 wild type transcripts, of which 1 are protein-coding. Following removal of the floxed region, 1 transcript is predicted to produce a truncated protein product of which 1 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000082254 protein_coding No protein product (NMD) view

Predicted translation:

MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEE
KMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRWMKSKPRTGSSFPWKKNWRLRRAMCRNSSFRRRLWMSSSSLSRRQSV
T*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000703281 UTR UTR
ENSMUSE00000873544 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000659470 CDS CDS
ENSMUSE00000659470 CDS Deleted
ENSMUSE00000509501 CDS CDS + stop codon + UTR
ENSMUSE00000659468 CDS
ENSMUSE00000915410 CDS
ENSMUSE00000625481 CDS
ENSMUSE00000659464 CDS
ENSMUSE00000659462 CDS
ENSMUSE00000659461 CDS
ENSMUSE00000659459 CDS
ENSMUSE00000659458 CDS
ENSMUSE00000243934 CDS
ENSMUSE00000625475 CDS
ENSMUSE00000625474 CDS
ENSMUSE00000572604 CDS
ENSMUSE00000142949 CDS
ENSMUSE00000142956 CDS
ENSMUSE00000142948 CDS
ENSMUSE00000403176 CDS
ENSMUSE00000625473 CDS + stop codon + UTR
ENSMUSE00000572603 UTR UTR
Legend: in frame deleted frameshifted

ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available