IKMC Project Report - EUCOMM (ID: 99954)

Qk MGI:97837 ENSMUSG00000062078
Pre-pipeline Designs Vectors ES Cells Mice
Vector Unsuccessful - Project Terminated

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 2 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000097414 protein_coding No protein product (NMD) view

Predicted translation:

MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEV*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000658321 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000269846 CDS Deleted
ENSMUSE00000269819 KH_dom_type_1 (29/29 aa) CDS CDS + stop codon + UTR
ENSMUSE00000269810 CDS
ENSMUSE00000434071 CDS
ENSMUSE00000434057 CDS
ENSMUSE00000658324 CDS
ENSMUSE00000658323 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000042296 protein_coding No protein product (NMD) view

Predicted translation:

MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEV*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000658321 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000269846 CDS Deleted
ENSMUSE00000269819 KH_dom_type_1 (29/29 aa) CDS CDS + stop codon + UTR
ENSMUSE00000269810 CDS
ENSMUSE00000434071 CDS
ENSMUSE00000434057 CDS
ENSMUSE00000508229 CDS + stop codon + UTR
Legend: in frame deleted frameshifted
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available