IKMC Project Report - EUCOMM (ID: 80459)

Oard1 MGI:2146818 ENSMUSG00000040771
Pre-pipeline Designs Vectors ES Cells Mice
Vector Construction in Progress

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 2 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000167180 protein_coding No protein product (NMD) view

Predicted translation:

MATRLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKRFGGVQELLSQHYKETGFTQANV*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000881824 UTR UTR
ENSMUSE00000485821 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000315604 A1pp (27/101 aa) CDS CDS
ENSMUSE00000657222 A1pp (20/101 aa) CDS Deleted
ENSMUSE00000438745 A1pp (38/101 aa) CDS CDS + stop codon + UTR
ENSMUSE00000909825 A1pp (18/101 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000046651 protein_coding No protein product (NMD) view

Predicted translation:

MATRLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKRFGGVQELLSQHYKETGFTQANV*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000657223 UTR UTR
ENSMUSE00000485821 UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000315604 A1pp (27/101 aa) CDS CDS
ENSMUSE00000657222 A1pp (20/101 aa) CDS Deleted
ENSMUSE00000438745 A1pp (38/101 aa) CDS CDS + stop codon + UTR
ENSMUSE00000517271 A1pp (18/101 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available