The International Knockout Mouse Consortium (IKMC) has launched its official web site at www.knockoutmouse.org, formerly the URL for the Knockout Mouse Project (KOMP). This extended site, supported by the NIH and EU, now serves as the common web portal for access to information on knockout vectors, ES cells and mice available from the international high-throughput knockout projects: KOMP, EUCOMM, NorCOMM and TIGM. Stay tuned for future enhancements as the content continues to evolve. We welcome your comments and feedback.
Application deadline: 6 July 2012
Mouse Molecular Genetics (A Wellcome Trust Scientific Conference)
20-23 September 2011
Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Abstract deadline: 12 August
Registration deadline: 22 August
Wellcome Trust Genome Campus, Hinxton, Cambridge.
Deadline for applications: 8 July 2011
The IDCC has released the Martsearch interface (now visible as a tab) on the IKMC website:
Martsearch reads and searches many IKMC-related BioMarts to integrate IKMC knockout data with other mouse-related information.
Emphasis in future development will include enhancing the integration with high-throughput expression and phenotype data marts and services.
Martsearch relies on completely open data services, and is open-source ( https://github.com/i-dcc/martsearch ).
We have worked with MGI in registering KOMP and EUCOMM alleles and establishing official nomenclature. MGI now represents all alleles from KOMP and EUCOMM; for example,
IKMC allele information is updated on a weekly basis.
We have implemented an Advanced Search: As before, one can search for genes to look up the targeting pipeline status for these genes. In addition, one can now search for all genes that have reached a specific pipeline status in all or in specific IKMC pipelines.
We have streamlined and simplified the on-line KOMP project gene nomination form. Researchers can now link to the nomination form directly from the KOMP gene search results page. The form can be used to nominate a gene for a specific KOMP targeting strategy or to express interest in raising the priority of a gene that is already in the KOMP project but does not yet have vectors, ES cells, or mice ready for distribution.
To access the new gene nomination form, start with a gene search.
We have streamlined the display of search / browse results and developed new