IKMC Project Report - EUCOMM (ID: 82738)

Vdac3 MGI:106922 ENSMUSG00000008892
Pre-pipeline Designs Vectors ES Cells Mice
Vector Unsuccessful - Project Terminated

Mice no data available

Mutagenesis Predictions

This gene has 2 wild type transcripts, of which 2 are protein-coding. Following removal of the floxed region, 2 transcripts are predicted to produce a truncated protein product of which 2 may be subject to non-sense mediated decay (NMD). The original allele for this mutation is of type ''. The table below shows the predicted structure of the gene transcripts after application of Flp and Cre (forming a 'Knockout-First, Post-Flp and Cre - Deletion, No Reporter' allele - more information on IKMC alleles can be found here). Click the 'view' button for each transcript to see the full prediction for that transcript.

Ensembl transcript id Ensembl Biotype Floxed transcript description Details
ENSMUST00000179233 protein_coding No protein product (NMD) view

Predicted translation:

MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDN
TLGTEISWENKKEEWEIKGLL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000348963 UTR UTR
ENSMUSE00000259256 Porin_Euk (20/275 aa) UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00001059769 Porin_Euk (18/275 aa) CDS CDS
ENSMUSE00000133875 Porin_Euk (51/275 aa) CDS CDS
ENSMUSE00000133876 Porin_Euk (18/275 aa) CDS Deleted
ENSMUSE00000133863 Porin_Euk (77/275 aa) CDS CDS + stop codon + UTR
ENSMUSE00000133873 Porin_Euk (51/275 aa) CDS
ENSMUSE00000469438 Porin_Euk (20/275 aa) CDS
ENSMUSE00000706578 Porin_Euk (24/275 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
ENSMUST00000009036 protein_coding No protein product (NMD) view

Predicted translation:

MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNT
LGTEISWENKKEEWEIKGLL*

Ensembl Exon ID Pfam Domains WildType Floxed
ENSMUSE00000348963 UTR UTR
ENSMUSE00000259256 Porin_Euk (20/274 aa) UTR + start codon + CDS UTR + start codon + CDS
ENSMUSE00000133867 Porin_Euk (17/274 aa) CDS CDS
ENSMUSE00000133875 Porin_Euk (51/274 aa) CDS CDS
ENSMUSE00000133876 Porin_Euk (18/274 aa) CDS Deleted
ENSMUSE00000133863 Porin_Euk (77/274 aa) CDS CDS + stop codon + UTR
ENSMUSE00000133873 Porin_Euk (51/274 aa) CDS
ENSMUSE00000469438 Porin_Euk (20/274 aa) CDS
ENSMUSE00000706578 Porin_Euk (24/274 aa) CDS + stop codon + UTR
Legend: in frame deleted frameshifted
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ES Cell Clones no data available

Targeting Vectors no data available

Intermediate Vectors no data available